What Are Polynucleotides (PDRN)?
Polynucleotides, often referred to as PDRN (polydeoxyribonucleotide), are DNA fragments derived from salmon or trout sperm that have powerful skin-repairing and anti-inflammatory properties. They work by stimulating fibroblasts and cellular receptors to promote tissue regeneration, increase collagen production, and improve skin hydration and elasticity.
How PDRN Is Used in Aesthetics
In cosmetic procedures, PDRN is commonly injected into the skin using microinjections or combined with microneedling. It is used to:
- Improve skin texture, tone, and hydration
- Support wound healing and post-procedure recovery
- Treat acne scars, fine lines, and dull, damaged skin
- Calm inflammation and improve barrier function
Why It’s Popular
PDRN is favored for its gentle yet effective regenerative action, especially for clients with sensitive, inflamed, or aging skin.
It offers visible rejuvenation with minimal irritation and downtime, making it a popular choice for skin boosters and biorevitalization treatments.
PDRN vs. Exosomes vs. PRP – What’s the Difference?
PDRN (Polynucleotides)
Acts as a stimulator, encouraging your skin to heal and regenerate by promoting collagen production and reducing inflammation. Great for hydration, healing, and skin recovery, especially in sensitive or aging skin.
Exosomes
Exosomes are cellular messengers that directly deliver growth factors, proteins, and genetic signals. They offer the most advanced and targeted regeneration, improving skin structure, tone, and healing at a deep cellular level.
PRP (Platelet-Rich Plasma)
PRP (Platelet-Rich Plasma) uses your own blood to stimulate collagen and healing. While natural and widely used, results can vary depending on your health and age. It’s effective, but less consistent than exosomes or PDRN.
Medical-Grade Skin Care Products and Beauty Aides & Treatments
Northeast Medical Aesthetics offers for sale, quality, medical-grade skin-care products, creams, serums, topical applications and beauty aides that we feel may provide the benefits a customer may use in confidence.